Nephroprotection of Withania somnifera root extract against gentamicin induced nephrotoxicity: a histological evaluation in experimental Wistar rats
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منابع مشابه
Protective effect of Withania somnifera dunal root extract against protracted social isolation induced behavior in rats.
This study investigated the effect of Withania somnifera Dunal (WS) root extract and diazepam in social isolation induced behavior such as anxiety and depression in rats. Rats were isolated for 6 weeks and the assessment of changed behavior were done on elevated plus maze (EPM) and forced swim test (FST). Isolation reared rats spent less time into the open arms on EPM and significantly increase...
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In this study the use of plants for medicinal purpose used locally in the treatment of various diseases and we examined for their antioxidant activity. Therefore, the present investigation is part of continuing programme related to the biochemical screening of local plants used in Ancient Indian Medicine, Ayurveda, Siddha and Yunani. An Aqueous root extract of Withania Somnifera (L.) Dunal (Ash...
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AIM Gentamycin, a widely-used aminoglycoside antibiotic, is recognized as possessing significant nephrotoxic potential in human beings. Gentamycin-induced nephrotoxicity is suggested to be mediated via reactive oxygen species. The present study investigated the possible antioxidant nephroprotective effect of lacidipine as a calcium-channel blocker in a gentamycin-induced nephrotoxicity model in...
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The present study is designed to investigate effect of Ashwagandha aqueous seed extract against pilocarpine-induced convulsions in rats. Convulsions was induced by pilocarpine injection (300mg/kg, i.p.). After 15 days, the animals were received carbamazepine (100 mg/kg) and Ashwagandha (25 & 50 mg/kg, orally), for 14 days. Death, latencies to the first convulsion and cholinergic signs were obse...
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Objective: The main objective of the current study was to observe the ameliorative effect of Withania somnifera on arsenic-induced testicular toxicity by exploring the crucial parameters such as sperm counts, sperm motility, hormonal assay and lipid peroxidation including histopathology. Materials and Methods: In the present study, arsenic in the form of sodium arsenite was administered orally ...
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ژورنال
عنوان ژورنال: International Journal of Basic & Clinical Pharmacology
سال: 2019
ISSN: 2279-0780,2319-2003
DOI: 10.18203/2319-2003.ijbcp20194275